On behalf of the organizing committee, we are pleased to announce that The Second International Conference on Computational Mathematics and Engineering Sciences (CMES2017) will be held from May 20 to 22, 2017 in Istanbul, Turkey. CMES2017 provides an ideal academic platform for  researchers and professionals to discuss recent developments in both theoretical, applied mathematics and engineering sciences. This event aims also to stimulate interactions between researchers in the field of computational mathematics and their applications in science and engineering, to present the development reached in this areas, and to showcase the computational expertise of our invited speakers and participants.