The rapid development of information technology and computer science takes human society toward smart environments. In the smart environments, anything that can assist to solve the current challenges in business, industry, science, daily life etc., can refer to ‘Smart X’. Smart X includes smart city, smart home, smart grids, smart building, smart forest, smart geosciences, and smart computing, etc. Smart X can help human in various dimensions, e.g., better living with better resources, faster and better decision making, more precise future predicting, and quicker response making to challenges in surrounding environments and so on. However, how to implement Smart X? Today, smart techniques, together with the advances in big data and high-performance computing power, offer us big opportunities and transformative potential for intelligent decisions and predictive services. The major challenges we are facing involves extracting valuable knowledge from big data i.e. smart data for smart X, studying creative computing theories and techniques for Smart X, and designing dynamic and globally cooperative infrastructure built upon Smart X. Smart X also leads to a dramatic paradigm shift in our scientific research towards smart-driven computing.