The 2015 Gordon Conference on Molecular Membrane Biology will feature cutting-edge research on organelle biology and membrane traffic, with fundamental implications across many areas of human health and development. Invited talks will cover a wide range of topics including membrane protein insertion and translocation; mechanisms and regulation of membrane shaping, fission, and fusion; the molecular basis of organellar identity and interactions; lipid biology; and metabolism and autophagy. In addition, two sessions will be devoted to new frontiers in molecular membrane biology. A longstanding strength of this Gordon Conference has been the multidisciplinary nature of the research reported, drawing on methodological advances in areas ranging from high-throughput genetics and proteomics to structural biology and super-resolution microscopy. Attendance by under-represented minorities, students, postdoctoral fellows, junior faculty, and faculty from primarily undergraduate institutions is encouraged. In addition to the 34 invited talks, 15 short talks will be presented by Conference participants selected on the basis of submitted abstracts. All applicants are therefore encouraged to submit a brief abstract describing their work and to indicate whether they would like their abstract to be considered for one of the short talks. For full consideration, applicants interested in presenting a short talk should submit their application by April 6, 2015. Alternatively, ample space and time will be afforded for the presentation and discussion of posters by all Conference attendees. Prior to and in association with the Gordon Research Conference, there will be a Gordon Research Seminar on Molecular Membrane Biology for students and postdoctoral researchers. In this forum, younger researchers will have the opportunity to present their work in talks and posters and to build collaborations and informal networks with their peers prior to the arrival of senior investigators. Interested trainees can find more information here.