The Mammary Gland Biology Gordon Research Conference brings together a fascinating blend of scientists interested in the molecular and cellular mechanisms governing normal mammary gland development, physiology and cancer. This meeting provides unique opportunities to engage with experts and learn about breaking concepts and specialized techniques in these research areas. Focus areas for the 2015 conference include functional imaging of breast, mammary circulatory systems (including lymphangiogenesis), metabolic regulation of mammary epithelial cells, modulation by stress responses, interactions between adipocytes and mammary epithelium, breast cancer risk and prevention, and immune regulation of normal breast and breast tumor development. This conference is designed to promote the careers of young scientists, and includes “Lunch with the expert” to provide mentoring and perspective. Overall, there is a notably collegial and friendly tone. Lively poster sessions and opportunities for gathering during free time make this conference an engaging way to catch up with breaking news in basic and translational mammary-associated topics. We have reserved short talks in each session to highlight the most exciting work by young investigators and trainees, and these presentations will be chosen from the submitted abstracts. This GRC will be preceded by the next in a series of highly successful Mammary Gland Gordon Research Seminars; graduate students and junior post-docs are encouraged to apply for both meetings.