The 21st annual IEEE International Conference on High Performance Computing (HiPC 2014) will be held at the Hotel Cidade De Goa in Goa, India, during December 17-December 20, 2014. It will serve as a forum for researchers from around the world to present their current research efforts and findings, and will act as a venue for stimulating discussions and highlighting high performance computing (HPC) related activities in Asia. The conference has a history of attracting participation from reputed researchers from all over the world. Day 1 of the conference will feature a Student Research Symposium and several Academic Birds-of-a-Feather (BOF) sessions. The technical program, held on Days 2, 3 and 4, will feature three invited keynote speakers and eight single track sessions of peer reviewed papers, and Day 4 will include a special Indo-US workshop. On Days 2 and 3, there will be a full program of Industry Events & Exhibits. In addition to the four day conference program, the HiPC 2014 venue will allow other HPC community events to take place on December 16th, the day before the conference. HiPC receives strong industry support from companies operating globally and also established in India. In addition to the two days of industry exhibits, the sponsoring partners to the conference hold industry symposiums to bring together providers and users of HPC in a forum for presenting state-of-the-art in HPC platforms and technologies, for discussing best practices, and for exchanging experiences.