The 22nd SPE Reservoir Simulation Symposium (RSS) will be held from Monday through Wednesday, 23 – 25 February 2015 in Houston, Texas, USA. As program chairperson, I invite you and your colleagues to submit abstracts to be considered for the symposium. Topics of major interest, as determined by the program committee, are listed here. If you have original results on any of these topics that have not been previously presented or published, please submit an abstract for consideration. Abstracts will be accepted online from 11 February 2014 through 23 June 2014. The committee will review abstracts for presentation in technical sessions and for presentation as posters. Qualified presentations and posters both require a full manuscript and will be included in the Proceedings. The committee members look forward to receiving your paper proposals and to seeing you at the symposium.