The Internet-of-Things (IoT) will revolutionize industry and our lives. Future IoT networks will need to provide low latency and high reliability communications for multiple vertical industries including transport, healthcare, manufacturing, agriculture and energy. Wireless technologies will be the most cost-effective and scalable solution for enabling the intensive acquisition of information from fixed and mobile IoT devices. However, many open questions still need to be addressed to overcome fundamental constraints of radio spectrum, power, and transmission distance to support secure wide area coverage and ultra-reliable low latency communications for IoT devices. Furthermore, it is expected that each vertical industry will need to share a common IoT platform and there are formidable challenges in unifying existing networks. These include massive computational complexity and transmission latency for data processing and management of massive number of terminals from multiple vertical industries, which are not adequately addressed in the latest 5G wireless network standard. As such, there is a need to redesign wireless access technologies and architectures with reconfigurable software-defined networks to facilitate a flexible and highly-scalable common IoT platform.