Abstract: This paper focuses on the complex scheduling problem due to resource constraints and non-negligible resource transfer time in the logistics scheduling domain, transforms this problem into the Resource Constrained Project Scheduling Problem with Resource Transfer Time (RCPSPTT), and proposes a solution algorithm integrating the Multi-Objective Grey Wolf Optimizer (MOGWO) and the A-Star algorithm. Firstly, the RCPSPTT model for logistics scheduling is established based on the constraint relationships among tasks, multiple resource constraints and resource transfer times in logistics scheduling, whereas the resource transfer times are calculated based on the accuracy of the A* algorithm, and the MOGWO algorithm with dual coding and modification of operators is used to solve the Pareto solution set with the optimization objective of minimizing the total time and the load balancing degree. Finally, a large-scale logistics project is used as a case study to verify the effectiveness of the proposed method in solving complex logistics scheduling problems, and provide a scientific optimization scheme for real logistics scheduling scenarios.